Weight Management

Compounded Tirzepatide

Compounded GIP/GLP-1
4,000+ Reviews

Tirzepatide is a first-in-class dual receptor agonist medication that mimics two hormones — GLP-1 and GIP. It works by slowing digestion, stimulating insulin production, and reducing sugar production in the liver.

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Frequency:Twice weekly
From $249/month (4-week supply)

What is Tirzepatide?

Tirzepatide is a dual GIP and GLP-1 receptor agonist. Unlike single-mechanism medications, it targets two pathways involved in appetite regulation and metabolism. This combined action has been shown to deliver greater mean weight loss than GLP-1-only therapy in head-to-head studies.

How effective is Tirzepatide?

Patients at Dr. Frank's tend to lose up to 20% of their body weight in the first year. A 40-week clinical study found Tirzepatide 15 mg delivered roughly double the mean weight reduction of Semaglutide 1 mg. Most patients begin to feel benefits within the first couple of weeks.

How to take Tirzepatide

You can inject Tirzepatide into your abdomen, thigh, or upper arm once weekly. We recommend alternating injection sites to prevent irritation. Our care team is on hand to answer any ongoing questions about your treatment.

Am I eligible for Tirzepatide?

Tirzepatide is authorized for patients with a BMI of 30 or above, or a BMI of 27 or above if you have a weight-related comorbidity. BMI criteria may be adjusted based on ethnicity. During the consultation, your provider will review your medical history to confirm it's a safe option for you.

References

Dr. Frank's Method

What's included

Weight Loss Medication

Discover the science behind GLP-1, our innovative medication designed to target three fundamental mechanisms for optimal weight management.

Licensed Healthcare Professionals

Our professional and licensed team is with you every step of the way — board-certified providers credentialed in your state.

Diet & Nutrition Support Pack

Accelerate your results and make informed decisions. Developed by Dr. Franklin Joseph and our specialist dietitian.

Compare treatments

Tirzepatide

Lose up to 22.5% of your body weight
MechanismDual GIP + GLP-1 receptor agonist
Average weight lossUp to 22.5%
Injection frequencyOnce weekly
Available doses2.5 / 5 / 7.5 / 10 / 12.5 / 15 mg

Semaglutide

Lose up to 15% of your body weight
MechanismGLP-1 receptor agonist
Average weight lossUp to 15%
Injection frequencyOnce weekly
Available doses0.25 / 0.5 / 1 / 1.7 / 2.4 mg
Why Dr. Frank's

Dr. Frank's Method vs Others

Dr. Frank's
Other programs
Led by a specialist

Dr. Frank, an endocrinology expert, leads the program.

Limited experience

Fewer years in the weight management field.

Rich expertise

15+ years of specialized experience in weight management.

General guidance

Often lacks specialized, expert-led oversight.

Tailored plans

Custom plans allow rapid dosage adjustments for faster results.

One-size-fits-all plans

Generic plans with slow, fixed dosing schedules.

Unlimited support

Access to unlimited ticketing and email support from healthcare professionals.

Restricted access

Limited support, often only via email or chat.

Quarterly video check-ins

With asynchronous monthly questionnaires in between — no video required.

Infrequent monitoring

Less frequent or no personal progress reviews.

How to Take Compounded Tirzepatide

You can inject Compounded Tirzepatideinto your abdomen, thigh or upper arm. We recommend alternating your injection sites to prevent irritation. Here’s a step-by-step on how to take Compounded Tirzepatide:

1
Select your injection site

Before you receive your medication, we’ll give you all the information you need to administer your injections safely. Our team is on hand at all times to answer any ongoing questions or concerns about your treatment.

Am I Eligible for Compounded Tirzepatide?

Compounded Tirzepatide is authorized for patients with a BMI (body mass index) higher than 30, or a BMI over 27 if you have a condition related to your weight. The BMI criteria may be lower depending on your ethnicity. So, you may be eligible for Compounded Tirzepatide if:

  • Tried diet and exercise without success
  • Your BMI is higher than 25

Chat with us today to determine whether Compounded Tirzepatidewill be a good fit for you. During the consultation, we’ll request information about your medical history to ensure that it is a safe option for you.

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How Effective is Compounded Tirzepatide?

In short, Compounded Tirzepatide is considered very effective. It works by affecting your appetite, making you feel fuller for longer. Ultimately, this will help you lose weight over time.

  • In the SURMOUNT-1 clinical trial, patients lost up to 22.5% of their body weight
  • In the SURMOUNT-1 clinical trial, patients lost 15.7% of their body weight (on 15mg)
  • In another study, patients on a higher dose (15mg) lost 21 lbs; patients on a lower dose (5mg) lost 11.6 lbs

Researchers estimate that people can lose up to 26.6% of their body weight on the highest dose, which is an average weight loss of 60 pounds in under two years. The results appear to be more impressive than other GLP-1 medications.

It can take 8–12 weeks to start seeing results, but most patients feel benefits within the first couple of weeks. At Dr. Frank's, our patients tend to lose up to 20% of their body weight in the first year.

Jacqui42 lbs · 5 months
I'm at my honeymoon weight, which was in April 1978.
Ethan70 lbs · 5 months
I've never felt so comfortable in my own skin.
Dimitra56 lbs · 8 months
The sole solution that's been effective after my long struggle.

FAQs

If you can’t find the answer you’re looking for, make sure to check our help centre

To join Dr Frank’s Weight Loss Clinic, you have a selection of options to choose from. Please follow these steps:

1. Explore our website and services to begin your understanding of what you can choose from. The team can also help as required.

2. Select Start Assessment. You will be presented with three options to begin your journey:

a. Complete our online assessment to determine your eligibility. You’ll then see a selection of subscription options to choose from.
b. Schedule a free video consultation with one of our specialist nurses to discuss the program in detail.
c. Book an in-clinic appointment at one of our Digital Hubs to discuss the program further and finalize your medical questionnaire.

GIP and GLP-1 medications, paired with our expert coaching, have consistently delivered impressive results in helping individuals achieve their weight loss goals. Within the first six months, many have experienced up to 10% weight loss.

Rest assured, your journey to better health is both effective and safe. These medications, prescribed and monitored by our medical experts, are generally well-tolerated.

Our dedicated medical team will guide and oversee your treatment, ensuring your safety and success.

As humans, we’re all different, so the amount of time can vary from person to person. However, most people do start seeing results within the first few weeks of treatment, even before reaching therapeutic doses.

Based on a 72-week clinical study, customers could lose up to 20% of their body weight on once-weekly tirzepatide compared to placebo.

As a general guide, most people taking semaglutide for weight loss are expected to lose at least 5% of their body weight within 12 weeks. If you don’t hit that milestone, our specialist nurses can arrange a referral to our specialist dietitians and life coaches.

Our systems and specialist nurses will calculate and review your BMI upon receipt of your application. You can also use our BMI calculator to work it out yourself.

BMI = Weight (lbs) / [Height (inches)]² × 703. A healthy BMI sits between 18.5 and 24.9.

Yes, certain medical conditions may disqualify someone from receiving medications like compounded semaglutide or tirzepatide. These medications contain specific active ingredients and may not be suitable for everyone.

Pregnancy and Breastfeeding: These medications may not be recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant.

Severe Gastrointestinal Disorders: Conditions such as inflammatory bowel disease (IBD) may make the use of these medications problematic.

History of Pancreatitis: Individuals with a history of pancreatitis may be at increased risk of recurrence.

No. Doses are titrated up gradually under clinical guidance to minimize side effects and find the lowest effective dose for you.

GLP-1 medications are prescription-only. A US-licensed clinician reviews your intake form and verifies eligibility before any medication is dispensed. That’s how we make sure the treatment is safe and appropriate for you.

Most clinical reviews complete within 24-48 hours of submitting your assessment. If you’ve booked a consultation, your clinician will confirm eligibility during the call.

Ready to start?

Begin your eligibility assessment for Compounded Tirzepatide. It takes about five minutes.

Start Assessment